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Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy

[Image: see text] The central dogma of the action of current anticancer drugs is that the drug tightly binds to its molecular target for inhibition. The reliance on tight ligand–receptor binding, however, is also the major root of drug resistance in cancer therapy. In this article, we highlight enzy...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533114/
https://www.ncbi.nlm.nih.gov/pubmed/25933032
http://dx.doi.org/10.1021/acs.bioconjchem.5b00196