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TRPA1 mediates the hypothermic action of acetaminophen
Acetaminophen (APAP) is an effective antipyretic and one of the most commonly used analgesic drugs. Unlike antipyretic non-steroidal anti-inflammatory drugs, APAP elicits hypothermia in addition to its antipyretic effect. Here we have examined the mechanisms responsible for the hypothermic activity...
Autores principales: | Gentry, Clive, Andersson, David A., Bevan, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533162/ https://www.ncbi.nlm.nih.gov/pubmed/26227887 http://dx.doi.org/10.1038/srep12771 |
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