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Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction
CD6 is a transmembrane protein with an extracellular region containing three scavenger receptor cysteine rich (SRCR) domains. The membrane proximal domain of CD6 binds the N-terminal immunoglobulin superfamily (IgSF) domain of another cell surface receptor, CD166, which also engages in homophilic in...
Autores principales: | Chappell, Paul E., Garner, Lee I., Yan, Jun, Metcalfe, Clive, Hatherley, Deborah, Johnson, Steven, Robinson, Carol V., Lea, Susan M., Brown, Marion H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533223/ https://www.ncbi.nlm.nih.gov/pubmed/26146185 http://dx.doi.org/10.1016/j.str.2015.05.019 |
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