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Discovery of an Unconventional Centromere in Budding Yeast Redefines Evolution of Point Centromeres

Centromeres are the chromosomal regions promoting kinetochore assembly for chromosome segregation. In many eukaryotes, the centromere consists of up to mega base pairs of DNA. On such “regional centromeres,” kinetochore assembly is mainly defined by epigenetic regulation [1]. By contrast, a clade of...

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Detalles Bibliográficos
Autores principales: Kobayashi, Norihiko, Suzuki, Yutaka, Schoenfeld, Lori W., Müller, Carolin A., Nieduszynski, Conrad, Wolfe, Kenneth H., Tanaka, Tomoyuki U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533239/
https://www.ncbi.nlm.nih.gov/pubmed/26166782
http://dx.doi.org/10.1016/j.cub.2015.06.023