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Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells
A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533313/ https://www.ncbi.nlm.nih.gov/pubmed/26267334 http://dx.doi.org/10.1038/srep13047 |