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Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells

A role for bone-marrow-derived cells (BMDCs) in tissue repair and malignancy onset has been proposed, but their contribution is still debated. We tested the ability of BMDCs containing the inducible kras(V12) oncogene to initiate lung adenocarcinoma. For our experimental strategy, we reconstituted l...

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Detalles Bibliográficos
Autores principales: Belloni, Elena, Martin Padura, Ines, Gerbino, Elvira, Orecchioni, Stefania, Fusar Imperatore, Fulvia, Marighetti, Paola, Bertalot, Giovanni, Giuseppe Pelicci, Pier, Bertolini, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533313/
https://www.ncbi.nlm.nih.gov/pubmed/26267334
http://dx.doi.org/10.1038/srep13047