Evaluation of Neuronal Protective Effects of Xanthine Oxidoreductase Inhibitors on Severe Whole-brain Ischemia in Mouse Model and Analysis of Xanthine Oxidoreductase Activity in the Mouse Brain

Global cerebral ischemia and reperfusion (I/R) often result in high mortality. Free radicals play an important role in global cerebral I/R. Xanthine oxidoreductase (XOR) inhibitors, such as allopurinol, have been reported to protect tissues from damage caused by reactive oxygen species (ROS) by inhi...

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Detalles Bibliográficos
Autores principales: SUZUKI, Go, OKAMOTO, Ken, KUSANO, Teruo, MATSUDA, Yoko, FUSE, Akira, YOKOTA, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533390/
https://www.ncbi.nlm.nih.gov/pubmed/25744353
http://dx.doi.org/10.2176/nmc.oa.2013-0307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533390/
https://www.ncbi.nlm.nih.gov/pubmed/25744353
http://dx.doi.org/10.2176/nmc.oa.2013-0307

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