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Two single amino acid substitutions in the intervening region of Newcastle disease virus HN protein attenuate viral replication and pathogenicity
Among the proteins encoded by Newcastle disease virus (NDV), the attachment protein (HN) is an important determinant of virulence and pathogenicity. HN has been molecularly characterized at the protein level; however, the relationship between the molecular character of HN and the animal pathotype it...
Autores principales: | Liu, Bin, Ji, Yanhong, Lin, Zhongqing, Fu, Yuguang, Muhammad Dafallah, Rihab, Zhu, Qiyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533526/ https://www.ncbi.nlm.nih.gov/pubmed/26267791 http://dx.doi.org/10.1038/srep13038 |
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