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Triazolophostins: a library of novel and potent agonists of IP(3) receptors
IP(3) receptors are channels that mediate the release of Ca(2+) from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP(3) receptors, with the β-anomeric adenine contributing to the increased potency. The potency of Ad...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533600/ https://www.ncbi.nlm.nih.gov/pubmed/25869535 http://dx.doi.org/10.1039/c5ob00440c |