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Triazolophostins: a library of novel and potent agonists of IP(3) receptors

IP(3) receptors are channels that mediate the release of Ca(2+) from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP(3) receptors, with the β-anomeric adenine contributing to the increased potency. The potency of Ad...

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Detalles Bibliográficos
Autores principales:	Vibhute, Amol M., Konieczny, Vera, Taylor, Colin W., Sureshan, Kana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533600/ https://www.ncbi.nlm.nih.gov/pubmed/25869535 http://dx.doi.org/10.1039/c5ob00440c

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