Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells

Incomplete abolition of tumorigenicity creates potential safety concerns in clinical trials of regenerative medicine based on human pluripotent stem cells (hPSCs). Here, we demonstrate that conditionally replicating adenoviruses that specifically target cancers using multiple factors (m-CRAs), origi...

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Detalles Bibliográficos
Autores principales: Mitsui, Kaoru, Ide, Kanako, Takayama, Akiko, Wada, Tadahisa, Irie, Rie, Kosai, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533615/
https://www.ncbi.nlm.nih.gov/pubmed/26269798
http://dx.doi.org/10.1038/mtm.2015.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533615/
https://www.ncbi.nlm.nih.gov/pubmed/26269798
http://dx.doi.org/10.1038/mtm.2015.26

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