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Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors

The epithelial-to-mesenchymal transition (EMT) is a well-known prerequisite for cancer cells to acquire the migratory and invasive capacity, and to subsequently metastasize. Bufalin is one of the major active components of the traditional Chinese medicine Chan Su, and accumulating evidence has shown...

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Detalles Bibliográficos
Autores principales: ZHAO, LEI, LIU, SHIZHOU, CHE, XIAOFANG, HOU, KEZUO, MA, YANJU, LI, CE, WEN, TI, FAN, YIBO, HU, XUEJUN, LIU, YUNPENG, QU, XIUJUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533784/
https://www.ncbi.nlm.nih.gov/pubmed/26133118
http://dx.doi.org/10.3892/ijmm.2015.2268