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Mouse Mincle: Characterization as a Model for Human Mincle and Evolutionary Implications

Mincle, the macrophage-inducible C-type lectin also known as CLEC-4E, binds to the mycobacterial glycolipid trehalose dimycolate and initiates a signaling cascade by serving as a receptor for Mycobacterium tuberculosis and other pathogenic mycobacterial species. Studies of the biological functions o...

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Detalles Bibliográficos
Autores principales: Rambaruth, Neela D. S., Jégouzo, Sabine A. F., Marlor, Hayley, Taylor, Maureen E., Drickamer, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533885/
https://www.ncbi.nlm.nih.gov/pubmed/25884549
http://dx.doi.org/10.3390/molecules20046670