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PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer

Transforming Growth Factor β (TGFβ) has dual functions as both a tumor suppressor and a promoter of cancer progression within the tumor microenvironment, but the molecular mechanisms by which TGFβ signaling switches between these outcomes and the contexts in which this switch occurs remain to be ful...

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Detalles Bibliográficos
Autores principales: Agajanian, Megan, Campeau, Anaamika, Hoover, Malachia, Hou, Alexander, Brambilla, Daniel, Kim, Sa La, Klemke, Richard L., Kelber, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533969/
https://www.ncbi.nlm.nih.gov/pubmed/26267863
http://dx.doi.org/10.1371/journal.pone.0135748