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PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer
Transforming Growth Factor β (TGFβ) has dual functions as both a tumor suppressor and a promoter of cancer progression within the tumor microenvironment, but the molecular mechanisms by which TGFβ signaling switches between these outcomes and the contexts in which this switch occurs remain to be ful...
Autores principales: | Agajanian, Megan, Campeau, Anaamika, Hoover, Malachia, Hou, Alexander, Brambilla, Daniel, Kim, Sa La, Klemke, Richard L., Kelber, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533969/ https://www.ncbi.nlm.nih.gov/pubmed/26267863 http://dx.doi.org/10.1371/journal.pone.0135748 |
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