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Synthesis and Evaluation of Chloramphenicol Homodimers: Molecular Target, Antimicrobial Activity, and Toxicity against Human Cells

As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloramphenicol (CAM), a prototypical wide-spectrum antib...

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Detalles Bibliográficos
Autores principales: Kostopoulou, Ourania N., Magoulas, George E., Papadopoulos, Georgios E., Mouzaki, Athanasia, Dinos, George P., Papaioannou, Dionissios, Kalpaxis, Dimitrios L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533973/
https://www.ncbi.nlm.nih.gov/pubmed/26267355
http://dx.doi.org/10.1371/journal.pone.0134526