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Synthesis and Evaluation of Chloramphenicol Homodimers: Molecular Target, Antimicrobial Activity, and Toxicity against Human Cells
As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloramphenicol (CAM), a prototypical wide-spectrum antib...
Autores principales: | Kostopoulou, Ourania N., Magoulas, George E., Papadopoulos, Georgios E., Mouzaki, Athanasia, Dinos, George P., Papaioannou, Dionissios, Kalpaxis, Dimitrios L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533973/ https://www.ncbi.nlm.nih.gov/pubmed/26267355 http://dx.doi.org/10.1371/journal.pone.0134526 |
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