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MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway

BACKGROUND: We aimed to investigate whether miRNA-1908 is an oncogene in human glioblastoma and find the possible mechanism of miR-1908. METHODS: We investigated the growth potentials of miRNA-1908-overexpressing SW-1783 cells in vitro and in vivo. In order to identify the target molecule of miRNA-1...

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Detalles Bibliográficos
Autores principales: Xia, Xuewei, Li, Yong, Wang, Wenbo, Tang, Fang, Tan, Jie, Sun, Liyuan, Li, Qinghua, Sun, Li, Tang, Bo, He, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534015/
https://www.ncbi.nlm.nih.gov/pubmed/26265437
http://dx.doi.org/10.1186/s12943-015-0423-0