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A simplicial complex-based approach to unmixing tumor progression data
BACKGROUND: Tumorigenesis is an evolutionary process by which tumor cells acquire mutations through successive diversification and differentiation. There is much interest in reconstructing this process of evolution due to its relevance to identifying drivers of mutation and predicting future prognos...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534068/ https://www.ncbi.nlm.nih.gov/pubmed/26264682 http://dx.doi.org/10.1186/s12859-015-0694-x |