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A simplicial complex-based approach to unmixing tumor progression data

BACKGROUND: Tumorigenesis is an evolutionary process by which tumor cells acquire mutations through successive diversification and differentiation. There is much interest in reconstructing this process of evolution due to its relevance to identifying drivers of mutation and predicting future prognos...

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Detalles Bibliográficos
Autores principales: Roman, Theodore, Nayyeri, Amir, Fasy, Brittany Terese, Schwartz, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534068/
https://www.ncbi.nlm.nih.gov/pubmed/26264682
http://dx.doi.org/10.1186/s12859-015-0694-x