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Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies
A number of penicillin derivatives (4a-h) were synthesized by the condensation of 6-amino penicillinic acid (6-APA) with non-steroidal anti-inflammatory drugs as antimicrobial agents. In silico docking study of these analogues was performed against Penicillin Binding Protein (PDBID 1CEF) using AutoD...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534092/ https://www.ncbi.nlm.nih.gov/pubmed/26267242 http://dx.doi.org/10.1371/journal.pone.0135293 |