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Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies

A number of penicillin derivatives (4a-h) were synthesized by the condensation of 6-amino penicillinic acid (6-APA) with non-steroidal anti-inflammatory drugs as antimicrobial agents. In silico docking study of these analogues was performed against Penicillin Binding Protein (PDBID 1CEF) using AutoD...

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Detalles Bibliográficos
Autores principales:	Ashraf, Zaman, Bais, Abdul, Manir, Md. Maniruzzaman, Niazi, Umar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534092/ https://www.ncbi.nlm.nih.gov/pubmed/26267242 http://dx.doi.org/10.1371/journal.pone.0135293

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