In Vitro Glycoengineering of IgG1 and Its Effect on Fc Receptor Binding and ADCC Activity

The importance and effect of Fc glycosylation of monoclonal antibodies with regard to biological activity is widely discussed and has been investigated in numerous studies. Fc glycosylation of monoclonal antibodies from current production systems is subject to batch-to-batch variability. If there ar...

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Detalles Bibliográficos
Autores principales: Thomann, Marco, Schlothauer, Tilman, Dashivets, Tetyana, Malik, Sebastian, Avenal, Cecile, Bulau, Patrick, Rüger, Petra, Reusch, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534130/
https://www.ncbi.nlm.nih.gov/pubmed/26266936
http://dx.doi.org/10.1371/journal.pone.0134949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534130/
https://www.ncbi.nlm.nih.gov/pubmed/26266936
http://dx.doi.org/10.1371/journal.pone.0134949

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