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In Vitro Glycoengineering of IgG1 and Its Effect on Fc Receptor Binding and ADCC Activity
The importance and effect of Fc glycosylation of monoclonal antibodies with regard to biological activity is widely discussed and has been investigated in numerous studies. Fc glycosylation of monoclonal antibodies from current production systems is subject to batch-to-batch variability. If there ar...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534130/ https://www.ncbi.nlm.nih.gov/pubmed/26266936 http://dx.doi.org/10.1371/journal.pone.0134949 |