Cargando…

Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet

AMP-activated protein kinase (AMPK) plays an important role in insulin resistance, which is characterized by the impairment of the insulin-Akt signaling pathway. However, the time course of the decrease in AMPK and Akt phosphorylation in the liver during the development of obesity and insulin resist...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiwa, Mami, Yoneda, Masayasu, Okubo, Hirofumi, Ohno, Haruya, Kobuke, Kazuhiro, Monzen, Yuko, Kishimoto, Rui, Nakatsu, Yusuke, Asano, Tomoichiro, Kohno, Nobuoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534138/
https://www.ncbi.nlm.nih.gov/pubmed/26266809
http://dx.doi.org/10.1371/journal.pone.0135554