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In vitro evaluation of digestive and endolysosomal enzymes to cleave CML-modified Ara h 1 peptides

Ara h 1 is a major peanut allergen. Processing-induced modifications may modulate the allergenic potency of Ara h 1. Carboxymethyl lysine (CML) modifications are a commonly described nonenzymatic modification on food proteins. In the current study, we tested the ability of digestive and endolysosoma...

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Detalles Bibliográficos
Autores principales: Mattison, Christopher P, Dinter, Jens, Berberich, Matthew J, Chung, Si-Yin, Reed, Shawndrika S, Le Gall, Sylvie, Grimm, Casey C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534154/
https://www.ncbi.nlm.nih.gov/pubmed/26288719
http://dx.doi.org/10.1002/fsn3.215