Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target

Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly expressed in diverse human carcinomas and certain hematologic malignancies. The oncogenic MUC1 transmembrane C-terminal subunit (MUC1-C) functions in part by transducing growth and survival signals from cell surface receptors. However, lit...

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Detalles Bibliográficos
Autores principales: Raina, Deepak, Agarwal, Praveen, Lee, James, Bharti, Ajit, McKnight, C. James, Sharma, Pankaj, Kharbanda, Surender, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534190/
https://www.ncbi.nlm.nih.gov/pubmed/26267657
http://dx.doi.org/10.1371/journal.pone.0135156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534190/
https://www.ncbi.nlm.nih.gov/pubmed/26267657
http://dx.doi.org/10.1371/journal.pone.0135156

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