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Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target

Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly expressed in diverse human carcinomas and certain hematologic malignancies. The oncogenic MUC1 transmembrane C-terminal subunit (MUC1-C) functions in part by transducing growth and survival signals from cell surface receptors. However, lit...

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Detalles Bibliográficos
Autores principales:	Raina, Deepak, Agarwal, Praveen, Lee, James, Bharti, Ajit, McKnight, C. James, Sharma, Pankaj, Kharbanda, Surender, Kufe, Donald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534190/ https://www.ncbi.nlm.nih.gov/pubmed/26267657 http://dx.doi.org/10.1371/journal.pone.0135156

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