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A Novel Method for Inducing Amastigote-To-Trypomastigote Transformation In Vitro in Trypanosoma cruzi Reveals the Importance of Inositol 1,4,5-Trisphosphate Receptor

BACKGROUND: Trypanosoma cruzi is a parasitic protist that causes Chagas disease, which is prevalent in Latin America. Because of the unavailability of an effective drug or vaccine, and because about 8 million people are infected with the parasite worldwide, the development of novel drugs demands urg...

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Detalles Bibliográficos
Autores principales: Hashimoto, Muneaki, Morales, Jorge, Uemura, Haruki, Mikoshiba, Katsuhiko, Nara, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534300/
https://www.ncbi.nlm.nih.gov/pubmed/26267656
http://dx.doi.org/10.1371/journal.pone.0135726