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A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development
CHARGE syndrome is caused by spontaneous loss-of-function mutations to the ATP-dependant chromatin remodeller chromodomain-helicase-DNA-binding protein 7 (CHD7). It is characterised by a distinct pattern of congenital anomalies, including cardiovascular malformations. Disruption to the neural crest...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534312/ https://www.ncbi.nlm.nih.gov/pubmed/26102480 http://dx.doi.org/10.1016/j.ydbio.2015.06.017 |