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A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development

CHARGE syndrome is caused by spontaneous loss-of-function mutations to the ATP-dependant chromatin remodeller chromodomain-helicase-DNA-binding protein 7 (CHD7). It is characterised by a distinct pattern of congenital anomalies, including cardiovascular malformations. Disruption to the neural crest...

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Detalles Bibliográficos
Autores principales: Payne, Sophie, Burney, Matthew J., McCue, Karen, Popal, Nelo, Davidson, Sean M., Anderson, Robert H., Scambler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534312/
https://www.ncbi.nlm.nih.gov/pubmed/26102480
http://dx.doi.org/10.1016/j.ydbio.2015.06.017

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