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The Epidermal Growth Factor Receptor (EGFR / HER-1) Gatekeeper Mutation T790M Is Present in European Patients with Early Breast Cancer

The epidermal growth factor receptor (EGFR) is one of the major oncogenes identified in a variety of human malignancies including breast cancer (BC). EGFR-mutations have been studied in lung cancer for some years and are established as important markers in guiding therapy with tyrosine kinase inhibi...

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Detalles Bibliográficos
Autores principales: Bemanian, Vahid, Sauer, Torill, Touma, Joel, Lindstedt, Bjørn Arne, Chen, Ying, Ødegård, Hilde Presterud, Vetvik, Katja Marjaana, Bukholm, Ida Rashida, Geisler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534377/
https://www.ncbi.nlm.nih.gov/pubmed/26267891
http://dx.doi.org/10.1371/journal.pone.0134398