Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at <100% neutralization. In the current study, we were interested in determini...

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Detalles Bibliográficos
Autores principales: McCoy, Laura E., Falkowska, Emilia, Doores, Katie J., Le, Khoa, Sok, Devin, van Gils, Marit J., Euler, Zelda, Burger, Judith A., Seaman, Michael S., Sanders, Rogier W., Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534392/
https://www.ncbi.nlm.nih.gov/pubmed/26267277
http://dx.doi.org/10.1371/journal.ppat.1005110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534392/
https://www.ncbi.nlm.nih.gov/pubmed/26267277
http://dx.doi.org/10.1371/journal.ppat.1005110

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