New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae

5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug, compromising its therapeutic action. The understanding of the underlying resistance mechanisms is crucial to deal with this problem. In this wo...

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Detalles Bibliográficos
Autores principales: Costa, Catarina, Ponte, Andreia, Pais, Pedro, Santos, Rui, Cavalheiro, Mafalda, Yaguchi, Takashi, Chibana, Hiroji, Teixeira, Miguel Cacho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534419/
https://www.ncbi.nlm.nih.gov/pubmed/26267134
http://dx.doi.org/10.1371/journal.pone.0135110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534419/
https://www.ncbi.nlm.nih.gov/pubmed/26267134
http://dx.doi.org/10.1371/journal.pone.0135110

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