Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells

BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...

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Detalles Bibliográficos
Autores principales: Rodrigues, Ana Sofia, Pereira, Sandro L., Correia, Marcelo, Gomes, Andreia, Perestrelo, Tânia, Ramalho-Santos, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534445/
https://www.ncbi.nlm.nih.gov/pubmed/26266544
http://dx.doi.org/10.1371/journal.pone.0135617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534445/
https://www.ncbi.nlm.nih.gov/pubmed/26266544
http://dx.doi.org/10.1371/journal.pone.0135617

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