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Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells

BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...

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Detalles Bibliográficos
Autores principales:	Rodrigues, Ana Sofia, Pereira, Sandro L., Correia, Marcelo, Gomes, Andreia, Perestrelo, Tânia, Ramalho-Santos, João
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534445/ https://www.ncbi.nlm.nih.gov/pubmed/26266544 http://dx.doi.org/10.1371/journal.pone.0135617

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