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Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells
BACKGROUND: Pluripotent embryonic stem cells grown under standard conditions (ESC) have a markedly glycolytic profile, which is shared with many different types of cancer cells. Thus, some therapeutic strategies suggest that pharmacologically shifting cancer cells towards an oxidative phenotype, usi...
Autores principales: | Rodrigues, Ana Sofia, Pereira, Sandro L., Correia, Marcelo, Gomes, Andreia, Perestrelo, Tânia, Ramalho-Santos, João |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534445/ https://www.ncbi.nlm.nih.gov/pubmed/26266544 http://dx.doi.org/10.1371/journal.pone.0135617 |
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