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DNA methylation analysis of benign and atypical meningiomas: correlation between RUNX3 methylation and WHO grade

PURPOSE: Although meningiomas are common central nervous system tumors, the biomarkers allowing early diagnosis and progression are still needed. The aim of this study was to evaluate the methylation status of 12 cancer-related genes, namely ERCC1, hMLH1, ATM, CDKN2B (p15INK4B), p14ARF, CDKN2A (p16I...

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Detalles Bibliográficos
Autores principales: Majchrzak-Celińska, Aleksandra, Paluszczak, Jarosław, Szalata, Marlena, Barciszewska, Anna-Maria, Nowak, Stanisław, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534508/
https://www.ncbi.nlm.nih.gov/pubmed/25648363
http://dx.doi.org/10.1007/s00432-015-1930-5