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Reduced SIRT1 expression correlates with enhanced oxidative stress in compensated and decompensated heart failure
Sirtuin-1 (SIRT1) is a longevity factor in mammals initiating the cell survival mechanisms, and preventing ischemic injury in heart. In the etiopathogenesis of heart failure (HF), impairment in cardiomyocyte survival is a notable factor. Oxidative stress comprises a critical impact on cardiomyocyte...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534572/ https://www.ncbi.nlm.nih.gov/pubmed/26233702 http://dx.doi.org/10.1016/j.redox.2015.07.011 |