Cargando…

Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis

In the PLATO study, ticagrelor was associated with fewer pulmonary infections and subsequent deaths than clopidogrel. Neutrophils are a first-line defence against bacterial lung infection; ticagrelor inhibits cellular uptake of adenosine, a known regulator of neutrophil chemotaxis and phagocytosis....

Descripción completa

Detalles Bibliográficos
Autores principales: Alsharif, Khalaf F., Thomas, Mark R., Judge, Heather M., Khan, Haroon, Prince, Lynne R., Sabroe, Ian, Ridger, Victoria C., Storey, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534709/
https://www.ncbi.nlm.nih.gov/pubmed/25869515
http://dx.doi.org/10.1016/j.vph.2015.02.006