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Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis
In the PLATO study, ticagrelor was associated with fewer pulmonary infections and subsequent deaths than clopidogrel. Neutrophils are a first-line defence against bacterial lung infection; ticagrelor inhibits cellular uptake of adenosine, a known regulator of neutrophil chemotaxis and phagocytosis....
Autores principales: | Alsharif, Khalaf F., Thomas, Mark R., Judge, Heather M., Khan, Haroon, Prince, Lynne R., Sabroe, Ian, Ridger, Victoria C., Storey, Robert F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534709/ https://www.ncbi.nlm.nih.gov/pubmed/25869515 http://dx.doi.org/10.1016/j.vph.2015.02.006 |
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