Cargando…

Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming

Hypothermia is potently neuroprotective but poor mechanistic understanding has restricted its clinical use. Rodent studies indicate that hypothermia can elicit preconditioning, wherein a subtoxic cellular stress confers resistance to an otherwise lethal injury. The molecular basis of this preconditi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rzechorzek, Nina Marie, Connick, Peter, Patani, Rickie, Selvaraj, Bhuvaneish Thangaraj, Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534756/
https://www.ncbi.nlm.nih.gov/pubmed/26287272
http://dx.doi.org/10.1016/j.ebiom.2015.04.004