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New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Drug hypersensitivity reactions are an important clinical problem for both health care and industry. Recent advances in genetics have identified a number of HLA alleles associated with a range of these adverse reactions predominantly affecting the skin but also other organs, such as the liver. The a...

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Detalles Bibliográficos
Autores principales: Pirmohamed, Munir, Ostrov, David A., Park, B. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534769/
https://www.ncbi.nlm.nih.gov/pubmed/26254050
http://dx.doi.org/10.1016/j.jaci.2015.06.022