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A critical role of toll-like receptor 2 (TLR2) and its’ in vivo ligands in radio-resistance

The role of Toll-like receptor-2 (TLR2) in radio-resistance remained largely unknown. TLR2 knockout (TLR2(−/−)) mice received radiation of 6.5 Gy, and then were studied. We found that radiation resulted in more severe mortality and morbidity rates in TLR2(−/−) mice. The cause of death in TLR2(−/−) m...

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Detalles Bibliográficos
Autores principales: Gao, Fu, Zhang, Chaoxiong, Zhou, Chuanfeng, Sun, Weimin, Liu, Xin, Zhang, Pei, Han, Jiaqi, Xian, Linfeng, Bai, Dongchen, Liu, Hu, Cheng, Ying, Li, Bailong, Cui, Jianguo, Cai, Jianming, Liu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534783/
https://www.ncbi.nlm.nih.gov/pubmed/26268450
http://dx.doi.org/10.1038/srep13004