A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

X-chromosome inactivation is the process that evolved in mammals to equalize levels of X-linked gene expression in XX females relative to XY males. Silencing of a single X chromosome in female cells is mediated by the non-coding RNA Xist. Although progress has been made toward identifying factors th...

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Detalles Bibliográficos
Autores principales: Moindrot, Benoit, Cerase, Andrea, Coker, Heather, Masui, Osamu, Grijzenhout, Anne, Pintacuda, Greta, Schermelleh, Lothar, Nesterova, Tatyana B., Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534822/
https://www.ncbi.nlm.nih.gov/pubmed/26190105
http://dx.doi.org/10.1016/j.celrep.2015.06.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534822/
https://www.ncbi.nlm.nih.gov/pubmed/26190105
http://dx.doi.org/10.1016/j.celrep.2015.06.053

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