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Phosphoinositide 3-kinase: friend and foe in cardiovascular disease

Class I phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases activated by cell membrane receptors, either receptor tyrosine kinases (RTKs) or G protein–coupled receptors (GPCRs), to catalyze the production of the lipid second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3). T...

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Detalles Bibliográficos
Autores principales: Ghigo, Alessandra, Li, Mingchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534856/
https://www.ncbi.nlm.nih.gov/pubmed/26321955
http://dx.doi.org/10.3389/fphar.2015.00169