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A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial

OBJECTIVES: Outer membrane vesicle (OMV) vaccines are used against outbreaks of capsular group B Neisseria meningitidis (MenB) caused by strains expressing particular PorA outer membrane proteins (OMPs). Ferric enterobactin receptor (FetA) is another variable OMP that induces type-specific bacterici...

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Detalles Bibliográficos
Autores principales: Marsay, L., Dold, C., Green, C.A., Rollier, C.S., Norheim, G., Sadarangani, M., Shanyinde, M., Brehony, C., Thompson, A.J., Sanders, H., Chan, H., Haworth, K., Derrick, J.P., Feavers, I.M., Maiden, M.C., Pollard, A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535279/
https://www.ncbi.nlm.nih.gov/pubmed/25982025
http://dx.doi.org/10.1016/j.jinf.2015.05.006