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Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression

BACKGROUND: Cellular senescence is linked to aging and tumorigenesis. The senescence of mesenchymal stem cells (MSCs) may influence the tumor growth, metastasis, and angiogenesis by secreting a variety of cytokines and growth factors. RESULTS: The conditioned media of adipose derived MSCs (AD-MSCs)...

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Detalles Bibliográficos
Autores principales: Li, Yanju, Xu, Xiao, Wang, Lihua, Liu, Guangjin, Li, Yanqi, Wu, Xiaobing, Jing, Yongguang, Li, Haiyan, Wang, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535282/
https://www.ncbi.nlm.nih.gov/pubmed/26273429
http://dx.doi.org/10.1186/s13578-015-0012-3