Statistical inference for extended or shortened phase II studies based on Simon’s two-stage designs

BACKGROUND: Simon’s two-stage designs are popular choices for conducting phase II clinical trials, especially in the oncology trials to reduce the number of patients placed on ineffective experimental therapies. Recently Koyama and Chen (2008) discussed how to conduct proper inference for such studi...

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Detalles Bibliográficos
Autores principales: Zhao, Junjun, Yu, Menggang, Feng, Xi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535394/
https://www.ncbi.nlm.nih.gov/pubmed/26048655
http://dx.doi.org/10.1186/s12874-015-0039-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535394/
https://www.ncbi.nlm.nih.gov/pubmed/26048655
http://dx.doi.org/10.1186/s12874-015-0039-5

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