Cargando…
Using shRNA experiments to validate gene regulatory networks
Quantitative validation of gene regulatory networks (GRNs) inferred from observational expression data is a difficult task usually involving time intensive and costly laboratory experiments. We were able to show that gene knock-down experiments can be used to quantitatively assess the quality of lar...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535466/ https://www.ncbi.nlm.nih.gov/pubmed/26484195 http://dx.doi.org/10.1016/j.gdata.2015.03.011 |