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Genome-wide copy number profiling to detect gene amplifications in neural progenitor cells

DNA sequence amplification occurs at defined stages during normal development in amphibians and flies and seems to be restricted in humans to drug-resistant and tumor cells only. We used array-CGH to discover copy number changes including gene amplifications and deletions during differentiation of h...

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Detalles Bibliográficos
Autores principales: Fischer, U., Keller, A., Backes, C., Meese, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535527/
https://www.ncbi.nlm.nih.gov/pubmed/26484086
http://dx.doi.org/10.1016/j.gdata.2014.06.020