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Genome-wide copy number profiling to detect gene amplifications in neural progenitor cells
DNA sequence amplification occurs at defined stages during normal development in amphibians and flies and seems to be restricted in humans to drug-resistant and tumor cells only. We used array-CGH to discover copy number changes including gene amplifications and deletions during differentiation of h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535527/ https://www.ncbi.nlm.nih.gov/pubmed/26484086 http://dx.doi.org/10.1016/j.gdata.2014.06.020 |