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Bcl2 inhibition of mitochondrial DNA repair
BACKGROUND: Accumulation of mitochondrial DNA (mtDNA) damage could enhance the frequency of mitochondrial mutations and promote a variety of mitochondria-related diseases, including cancer. However, the mechanism(s) involved are not fully understood. METHODS: Quantitative extended length PCR was use...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535531/ https://www.ncbi.nlm.nih.gov/pubmed/26268226 http://dx.doi.org/10.1186/s12885-015-1594-1 |