High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients

Circulating tumour DNA (ctDNA) is an emerging field of cancer research. However, current ctDNA analysis is usually restricted to one or a few mutation sites due to technical limitations. In the case of massively parallel DNA sequencers, the number of false positives caused by a high read error rate...

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Detalles Bibliográficos
Autores principales: Kukita, Yoji, Matoba, Ryo, Uchida, Junji, Hamakawa, Takuya, Doki, Yuichiro, Imamura, Fumio, Kato, Kikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535617/
https://www.ncbi.nlm.nih.gov/pubmed/26126624
http://dx.doi.org/10.1093/dnares/dsv010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535617/
https://www.ncbi.nlm.nih.gov/pubmed/26126624
http://dx.doi.org/10.1093/dnares/dsv010

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